Monitoring allergen immunotherapy of pollen‐allergic patients: the ratio of allergen‐specific IgG4 to IgG1 correlates with clinical outcome
- 1 April 1999
- journal article
- clinical trial
- Published by Wiley in Clinical and Experimental Allergy
- Vol. 29 (4) , 497-506
- https://doi.org/10.1046/j.1365-2222.1999.00525.x
Abstract
Background Although allergen immunotherapy has been established as a treatment of type I allergy back in 1911, until now the underlying mechanisms have not been fully understood, nor are there any p...Keywords
This publication has 42 references indexed in Scilit:
- Isotypic analysis of grass pollen-specific antibodies in human plasma. 4. Biological activity of allergen-specific and autoanti-IgE antibody fractions on basophil histamine releaseClinical and Experimental Allergy, 1996
- Clinical and immunological effects of immunotherapy with alum‐absorbed grass allergoid in grass‐pollen‐induced hay feverAllergy, 1992
- Group V allergens in grass pollens. II. Investigation of group V allergens in pollens from 10 grassesClinical and Experimental Allergy, 1991
- Regulation and deregulation of human IgE synthesisImmunology Today, 1990
- A placebo-controlled trial of immunotherapy with two extracts of Dermatophagoides pteronyssinus in allergic rhinitis, comparing clinical outcome with changes in antigen-specific IgE, IgG, and IgG subclassesJournal of Allergy and Clinical Immunology, 1990
- Immunological changes associated with a successful outcome of pollen immunotherapyAllergy, 1988
- High IgG4 antibody level is associated with failure of immunotherapy with inhalant allergensClinical and Experimental Allergy, 1987
- Application of allergen research to diagnosis and immunotherapyAllergy, 1985
- Generation of Antigen-Specific Suppressor Cells during Allergy DesensitizationNew England Journal of Medicine, 1980