Chemistry of Glucose and Biochemical Pathways of Biological Interest
Open Access
- 1 May 2000
- journal article
- research article
- Published by SAGE Publications in Peritoneal Dialysis International
- Vol. 20 (2_suppl) , 26-30
- https://doi.org/10.1177/089686080002002s06
Abstract
Glucose degradation, yielding GDPs, can take place in vivo or during heat treatment of glucose solutions. AGEs are formed from the interaction of D-glucose with reactive amino-acid side chains of proteins. Both GDPs and AGEs have been shown to impair cellular function. GDPs have additional damaging effects because they strongly promote AGE formation (as compared to D-glucose).Keywords
This publication has 8 references indexed in Scilit:
- Initiation of Dialysis: Current Trends and the Case for Timely InitiationPeritoneal Dialysis International, 2000
- N ε-(Carboxymethyl)Lysine Adducts of Proteins Are Ligands for Receptor for Advanced Glycation End Products That Activate Cell Signaling Pathways and Modulate Gene ExpressionJournal of Biological Chemistry, 1999
- Immunochemical detection of oxalate monoalkylamide, an ascorbate‐derived Maillard reaction product in the human lensFEBS Letters, 1999
- Role of oxidative stress in diabetic complications: a new perspective on an old paradigm.Diabetes, 1999
- Glucose Degradation and Cytotoxicity in Pd FluidsPeritoneal Dialysis International, 1996
- Mechanism of Protein Modification by Glyoxal and Glycolaldehyde, Reactive Intermediates of the Maillard ReactionJournal of Biological Chemistry, 1995
- New Aspects of the Maillard Reaction in Foods and in the Human BodyAngewandte Chemie International Edition in English, 1990
- Effects of 3-deoxyglucosone on the Maillard reactionClinical Chemistry, 1990