Identification of Threonine 66 as a Functionally Critical Residue of the Interleukin-1 Receptor-associated Kinase
Open Access
- 1 October 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (40) , 37414-37421
- https://doi.org/10.1074/jbc.m205160200
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Negative Regulation of Toll-like Receptor-mediated Signaling by TollipJournal of Biological Chemistry, 2002
- Ras Participates in the Activation of p38 MAPK by Interleukin-1 by Associating with IRAK, IRAK2, TRAF6, and TAK-1Journal of Biological Chemistry, 2002
- IRAK-mediated Translocation of TRAF6 and TAB2 in the Interleukin-1-induced Activation of NFκBJournal of Biological Chemistry, 2001
- The MAPK Kinase Kinase TAK1 Plays a Central Role in Coupling the Interleukin-1 Receptor to Both Transcriptional and RNA-targeted Mechanisms of Gene RegulationJournal of Biological Chemistry, 2001
- Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin ChainPublished by Elsevier ,2000
- The Interleukin-1 Receptor Accessory Protein (IL-1RAcP) Is Essential for IL-1-induced Activation of Interleukin-1 Receptor-associated Kinase (IRAK) and Stress-activated Protein Kinases (SAP Kinases)Journal of Biological Chemistry, 1997
- TRAF6 is a signal transducer for interleukin-1Nature, 1996
- The death domain motif found in Fas (Apo‐1) and TNF receptor is present in proteins involved in apoptosis and axonal guidanceFEBS Letters, 1995
- The death domain: a module shared by proteins with diverse cellular functionsTrends in Biochemical Sciences, 1995
- A novel domain within the 55 kd TNF receptor signals cell deathCell, 1993