Plasma Bupivacaine Concentrations following Lumbar Epidural Anaesthesia in Children
Open Access
- 1 May 1986
- journal article
- research article
- Published by SAGE Publications in Anaesthesia and Intensive Care
- Vol. 14 (2) , 131-134
- https://doi.org/10.1177/0310057x8601400205
Abstract
Plasma levels of bupivacaine were measured following lumbar epidural administration of 3 mg/kg of 0.5% plain solution in sixteen children. The peak levels were generally between 1.0 and 2 μg/ml, the highest being 2.9 μg/ml. No manifestations of toxicity were observed. There was a significant positive correlation between peak plasma levels and increasing age.Keywords
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