Geometric Selectivity of Pig Liver Esterase and its Application to the Separation of Fluorinated Bicyclic Esters

Abstract
The hydrolysis of exo-2-ethoxycarbonyl-7-oxabicyclo[2.2.1]hept-5-enes 1-3 by pig liver esterase is much faster than that of the endo isomers. This allows an easy separation of an endo - exo mixture on a preparative scale.

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