Species-specific uptake of DNA by gonococci is mediated by a 10-base-pair sequence
- 1 June 1991
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 173 (12) , 3911-3913
- https://doi.org/10.1128/jb.173.12.3911-3913.1991
Abstract
Piliated Neisseria gonorrhoeae are known to be transformed less readily if transforming DNA competes with DNA containing the 10-bp sequence GCCGTCTGAA. It has been postulated that the 10-bp sequence is a recognition sequence which is required for efficient DNA uptake. We show that the presence of various forms of this 10-bp sequence results in increased uptake of double-stranded DNA into a DNase-resistant state and allows genetic transformation by an otherwise nontransformable plasmid. ImagesKeywords
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