Correlation of Expression of H/LeY/LeBAntigens with Survival in Patients with Carcinoma of the Lung
Open Access
- 2 July 1992
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 327 (1) , 14-18
- https://doi.org/10.1056/nejm199207023270103
Abstract
The level of expression of H/Ley/Leb antigens is high in various histologic types of lung cancer, a feature that may be related to deletion of A and B blood-group antigens. We evaluated the possibility that expression of this antigen, which can be defined by the monoclonal antibody MIA-15–5, might be of prognostic value, as suggested by our previous observation that MIA-15–5 inhibits tumor-cell motility and metastasis.Keywords
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