Control of Insulin-Dependent Diabetes with Portable Miniaturized Infusion Systems
- 1 March 1980
- journal article
- research article
- Published by American Diabetes Association in Diabetes Care
- Vol. 3 (2) , 309-313
- https://doi.org/10.2337/diacare.3.2.309
Abstract
A method of insulin therapy that appears to achieve better control of diabetes than present conventional methods is the use of insulin infusion devices — either glucose-controlled feedback (closed-loop) systems or the preprogrammed (open-loop) infusion pump. In view of the problems with implantable glucose sensors, we have worked to develop a miniaturized, programmable infusion system. Its use in insulin-dependent diabetic patients to provide either intravenous doses or a continuous subcutaneous insulin infusion resulted in significant reductions in blood glucose levels, glycemic excursions and 24-h glucose excretion.Keywords
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