Subgroups of primary Sjögren’s syndrome. Sjögren’s syndrome in male and paediatric Greek patients

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Abstract
OBJECTIVES To describe the clinical and serological findings in male and paediatric Sjögren’s syndrome (SS) patients. PATIENTS AND METHODS Using the European criteria for the diagnosis of SS 12 male and 13 paediatric patients were identified and compared with those of 30 consecutive unselected adult female SS patients. RESULTS The mean (SD) age of paediatric patients was 9.4 (2.2) years, ranging from 6 to 14 years. Recurrent parotid gland enlargement was the initial clinical manifestation in the majority of the children with a statistical significance compared with male (pCONCLUSION Primary SS is rare in children and men in Greece. Recurrent parotid gland enlargement is the most common clinical finding at disease onset in children. Male patients seem to have less systemic manifestations and lower frequency of autoantibodies.

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