Cytogenetic Observations in Infertile Men Working with Insecticidal Compounds
- 1 January 1978
- journal article
- research article
- Published by Cambridge University Press (CUP) in Acta geneticae medicae et gemellologiae
- Vol. 27, 51-56
- https://doi.org/10.1017/s0001566000009508
Abstract
The negative influence of some insecticides on male fertility has been noted. We report our cytogenetic observations on a group of infertile insecticide workers. Increased chromosomal breakage was a constant finding and the Y chromosome was especially damaged. This may account for impaired spermatogenesis. Furthermore, the involvement of heterochromatic chromosomal variants both in the individual susceptibility to the chemically induced damage and in the reproductive fitness is emphasized.Keywords
This publication has 20 references indexed in Scilit:
- Mutagenic and recombinogenic action of pesticides in Aspergillus nidulansMutation Research/Environmental Mutagenesis and Related Subjects, 1977
- A correlative study on the genetic damage induced by chemical mutagens in bone marrow and spermatogonia of miceMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1976
- A comparative study of the frequencies of radiation-induced chromosome aberrations in somatic and germ cells of the rhesus monkey (Macaca mulatta)Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1976
- Sex-chromosome pairing and male fertilityCytogenetic and Genome Research, 1974
- X-Y chromosome dissociation and sterility in the mouseCytogenetic and Genome Research, 1973
- A simple technique for demonstrating centromeric heterochromatinExperimental Cell Research, 1972
- Meiotic studies on a subfertile patient with a ring Y chromosomeCytogenetic and Genome Research, 1971
- A gross reduction in chiasma formation during meiotic prophase and a defective DNA repair mechanism associated with a case of human male infertilityCytogenetic and Genome Research, 1970
- The timing of mitosis and meiosis in Allium ascalonicum: A problem of differentiationHeredity, 1955
- Asynapsis and spontaneous chromosome breakage in scillaHeredity, 1952