Liquid Chromatographic Determination of Ivermectin in Bovine Serum
- 1 January 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of AOAC INTERNATIONAL
- Vol. 72 (1) , 59
- https://doi.org/10.1093/jaoac/72.1.59
Abstract
A rapid, sensitive method is described for the determination of ivermectin concentrations in bovine serum. Ivermectin is extracted by passing a sample through a reverse-phase C18 cartridge. A silicapacked cartridge is used to purify the extract further. Ivermectin is quantitated by liquid chromatography with detection at 245 nm. Recoveries were 95 ± 4% for samples fortified with 20 ppb ivermectin. Concentrations as low as 2 ppb can be detected in 5 g samples.This publication has 2 references indexed in Scilit:
- Direct Determination of Avermectins in Plasma at Nanogram Levels by High-Performance Liquid ChromatographyJournal of Pharmaceutical Sciences, 1983
- Determination of ivermectin in cattle and sheep tissues using high-performance liquid chromatography with fluorescence detectionJournal of Agricultural and Food Chemistry, 1981