ON THE RATE OF SECRETION OF BILE

Abstract
In a healthy patient with a bile fistula, the rate of bile secretion was studied for 16 consecutive days. Secretion was more rapid in the waking hours than in sleeping. The composite values for the rates of secretion give a curve with 2 distinct maxima. There was no regular increased secretory activity following the ingestion of food. The secretory activity was more regular during the 2d 8 days of study than during the 1st. The sphincter of Oddi withstood a pressure of as much as 23 cm. of water before allowing the passage of fluid into the duodenum.

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