CROSS ANTIGENICITIES OF LEPTOSPIRA INTERROGANS SEROVAR COPENHAGENI SHIBAURA STRAIN FOR PREPARING BIOLOGICAL PRODUCTS IN JAPAN
- 1 January 1980
- journal article
- research article
- Published by Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis in Japanese Journal of Medical Science and Biology
- Vol. 33 (4) , 223-229
- https://doi.org/10.7883/yoken1952.33.223
Abstract
Cross protective antigenicities of Leptospira were studied with 16 antisera to 13 serovars of Leptospira interrogans and a virulent strain Shibaura (v), which is now considered to belong to serovar copenhageni, for challenge. The antisera of the rabbits highly immunized with various serovar live antigens were examined for leptospiricidal activity; cross immunity was recognized only in the same serogroup, L. icterohaemorrhagiae. Serovar icterohaemorrhagiae lacks a part of the antigenic components of copenhageni, but the antiserum to the former showed potent leptospiricidal activity to Shibaura (v). Anti-copenhageni immune serum absorbed with the icterohaemorrhagiae antigen did not show any protective activity to Shibaura (v).This publication has 3 references indexed in Scilit:
- IDENTIFICATION OF SOME JAPANESE LEPTOSPIRAL STRAINS AS SEROTYPES COPENHAGENI AND ICTEROHAEMORRHAGIAE BY PRECIPITIN-ABSORPTION TEST IN GEL1977
- STUDIES ON THE POTENCY TEST OF ANTISERUM FOR WEIL'S DISEASE BY THE INTRACUTANEOUS METHODJapanese Journal of Medical Science and Biology, 1975
- INTRACUTANEOUS INFECTION WITH LEPTOSPIRA ICTEROHAEMORRHAGIAE (SHIBAURA STRAIN) OF THE GUINEA PIGJapanese Journal of Medical Science and Biology, 1974