The structures of five new didehydropeptides related to neoechinulin, isolated from Aspergillus amstelodami
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 7,p. 713-717
- https://doi.org/10.1039/p19770000713
Abstract
Five new neoechinulin-type metabolites have been isolated from the mycelium of Aspergillus amstelodami, grown on molasses beet cultures. They are all characterised by a didehydrotryptophyl structure with a reversed isoprenic chain at the 2-position of the indole nucleus, and have been named neoechinulins A–E. On the basis of chemical and spectral evidence they have been shown to be, respectively, cyclo-alanyl-2-(1,1-dimethylprop-2-enyl)-didehydrotryptophyl (II), cyclo-didehydroalanyl-2-(1,1-dimethylprop-2-enyl)didehydrotryptophyl (III), cyclo-didehydroalanyl-2-(1,1-dimethylprop-2-enyl)-6-(3-methylbut-2-enyl)didehydrotryptophyl (IV), cyclo-alanyl-2-(1,1-dimethylprop-2-enyl)-6-(3-methylbut-2-enyl)didehydrotryptophyl (V), and cyclo-oxamyl-2-(1,1-dimethylprop-2-enyl)didehydrotryptophyl (VI).This publication has 0 references indexed in Scilit: