Abstract
The effect of a rapid infusion of 5–10 per cent (w/v) solution of ethanol on veins was studied in about 400 patients. The infusion of up to 550 ml was given rapidly over 4–5 minutes. An unacceptably high incidence of pain and of sequelae followed the use of 7 and 10 per cent (w/v) solutions while 5 and 6 per cent (w/v) carried the lowest incidence of side effects. These latter were too dilute for use in intravenous anaesthesia, and the 8 per cent w/v (10 per cent v/v) caused no higher incidence of sequelae than propanidid. Therefore it is acceptable for clinical use.

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