Neuronal Activity in Chronic Ferric Chloride Epileptic Foci in Cats and Monkey

Abstract
The firing patterns of neurons surrounding sites of FeCl3 injection were studied in 6 cats and 1 Macaca mulatta monkey. Although a few neurons fired in poorly structured bursts similar to what has been described for some neurons in alumina foci in monkeys, no well-formed bursts were recorded. In addition, EEG spikes were not recorded chronically in 2 cats, nor were EEG spikes recorded during corticography. The reliability of this preparation in cats as a model of chronic epilepsy was not confirmed.