Crystal Structure of Stefin A in Complex with Cathepsin H: N-terminal Residues of Inhibitors can Adapt to the Active Sites of Endo- and Exopeptidases
- 1 February 2003
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 326 (3) , 875-885
- https://doi.org/10.1016/s0022-2836(02)01432-8
Abstract
No abstract availableKeywords
Funding Information
- International Centre for Genetic Engineering and Biotechnology
- Ministrstvo za Izobraževanje, Znanost in Šport
This publication has 42 references indexed in Scilit:
- The cystatins: Protein inhibitors of cysteine proteinasesPublished by Wiley ,2001
- The N‐terminal region of cystatin A (stefin A) binds to papain subsequent to the two hairpin loops of the inhibitor. Demonstration of two‐step binding by rapid‐kinetic studies of cystatin A labeled at the N‐terminus with a fluorescent reporter groupProtein Science, 2000
- The Contribution of N-Terminal Region Residues of Cystatin A (Stefin A) to the Affinity and Kinetics of Inhibition of Papain, Cathepsin B, and Cathepsin LBiochemistry, 1999
- Crystal structure of the wild-type human procathepsin B at 2.5 Å resolution reveals the native active site of a papain-like cysteine protease zymogenJournal of Molecular Biology, 1997
- [20] Processing of X-ray diffraction data collected in oscillation modePublished by Elsevier ,1997
- Differences in specificity for the interactions of stefins A, B and D with cysteine proteinasesFEBS Letters, 1996
- Production, Inhibitory Activity, Folding and Conformational Analysis of an N-terminal and an Internal Deletion Variant of Chicken CystatinEuropean Journal of Biochemistry, 1994
- Studies on the Aminopeptidase Activity of Rat Cathepsin HEuropean Journal of Biochemistry, 1992
- Endo- and Aminopeptidase Activities of Rat Cathepsin H.CHEMICAL & PHARMACEUTICAL BULLETIN, 1992
- Protein Inhibitors of Cysteine Proteinases. I. Isolation and Characterization of Stefin, a Cytosolic Protein Inhibitor of Cysteine Proteinases from Human Polymorphonuclear GranulocytesHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1983