Genetic diversity of sapovirus in fecal specimens from infants and children with acute gastroenteritis in Pakistan
- 11 October 2004
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 150 (2) , 371-377
- https://doi.org/10.1007/s00705-004-0401-0
Abstract
Summary. A total of 517 fecal specimens collected from infants and children with acute gastroenteritis in Karachi city, Pakistan during 1990–1994 were examined for the presence of sapovirus by RT-PCR and sequence analysis methods. Sapovirus was identified in 17 of 517 (3.2%) specimens. Sapovirus was further clustered into three distinct genogroups (I, II and IV) and these presented 70.6%, 23.5% and 5.9%, respectively. Our results clearly indicated that sapovirus could be classified into 7 GI and 4 GII genotypes. It was noteworthy to point out that sapovirus detected among Pakistani infants and children with acute gastroenteritis demonstrated the great genetic diversity and presented novel sapovirus genotypes.Keywords
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