IMPORTANCE OF PRESSURE FACTORS IN THE GENESIS OF PULMONARY EDEMA FOLLOWING VAGOTOMY
- 29 February 1948
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 152 (3) , 585-588
- https://doi.org/10.1152/ajplegacy.1948.152.3.585
Abstract
Guinea pigs anesthetized with pentobarbital sodium and maintained on artificial positive pressure respiration were divided into 2 groups, one group being subjected to 6 mm. Hg respiration pressure and the other group to 20 mm. Hg pressure. In addition, each group was divided into 2 subgroups, one subgroup having bilateral cervical vagotomy and the other subgroup having intact vagi. At 6 mm. Hg pressure neither intact nor vagotomized guinea pigs developed pulmonary edema in 5-25 hrs. of artificial respiration but with 20 mm. Hg pressure both subgroups had massive pulmonary edema in 4 hrs. Under artificial respiration, pressure is the predominant factor determining pulmonary edema and vagotomy is without a significant effect.Keywords
This publication has 1 reference indexed in Scilit:
- LUNG EDEMA FOLLOWING BILATERAL VAGOTOMYThe Journal of Experimental Medicine, 1939