Genetic susceptibility to neural tube defect pregnancy varies with offspring phenotype
- 21 October 2003
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 64 (5) , 424-428
- https://doi.org/10.1034/j.1399-0004.2003.00161.x
Abstract
Neural tube defects (NTDs) have a well-established genetic basis, although no single genetic factor has been identified as a major risk factor in NTD susceptibility. A large number of association stu...Keywords
This publication has 24 references indexed in Scilit:
- Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defectsMolecular Genetics and Metabolism, 2003
- Study of MTHFR and MS polymorphisms as risk factors for NTD in the Italian populationJournal of Human Genetics, 2002
- Neural-Tube DefectsNew England Journal of Medicine, 1999
- Possible interaction of genotypes at cystathionine β‐synthase and methylenetetrahydrofolate reductase (MTHFR) in neural tube defectsClinical Genetics, 1999
- Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defectsAmerican Journal of Medical Genetics, 1999
- The C677T mutation of the 5,10-methylenetetrahydrofolate reductase gene is a moderate risk factor for spina bifida in Italy.Journal of Medical Genetics, 1998
- Susceptibility to spina bifida; an association study of five candidate genesAnnals of Human Genetics, 1998
- 5,10 Methylenetetrahydrofolate reductase genetic polymorphism as a risk factor for neural tube defectsAmerican Journal of Medical Genetics, 1996
- Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifidaThe Lancet, 1995
- Do familial neural tube defects breed true?Journal of Medical Genetics, 1991