Design of a multislit, variable width collimator for microplanar beam radiotherapy

Abstract
Microbeam radiation therapy of the intracerebral 9L gliosarcoma in rats, an experimental surrogate for human malignant gliomas, using mainly 30–130 keV wiggler‐generated x rays, extended the residual lifespans of some rats ten or more times over those of untreated, similar gliosarcoma‐bearing rats. The rats were exposed 300 or 600 times to an upright, 25‐μm‐wide, 4‐mm‐high x‐ray beam. A multislit collimator has been designed to shorten the time required for the therapy.

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