Experimental Induction of Proteus mirabilis Cystitis in the Pony and Evaluation of Therapy with Trimethoprim-Sulfadiazine
Open Access
- 1 July 1981
- journal article
- research article
- Published by American Veterinary Medical Association (AVMA) in American Journal of Veterinary Research
- Vol. 42 (7) , 1203-1205
- https://doi.org/10.2460/ajvr.1981.42.07.1203
Abstract
SUMMARY: Proteus mirabilis cystitis was induced in 9 ponies by chemically eroding the bladder mucosa before the organism was inoculated. Comparisons were made in the treatment of P mirabilis cystitis between ponies treated daily for 13 days with a trimethoprim-sulfadiazine (tmp-sdz) paste and both positive and negative controls. Urine cultures from ponies treated with tmp-sdz became negative for P mirabilis between days 3 and 9 after the start of the treatment, whereas positive controls remained infected until day 13. Urine cultures from all ponies were negative for P mirabilis on day 28. Urine concentrations of tmp and sdz were relatively high after day 1 of therapy.This publication has 3 references indexed in Scilit:
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