Influence of Histamine in a Liver Injury Model Induced by Propionibacterium acnes and Lipopolysaccharide
- 1 January 2003
- journal article
- research article
- Published by Pharmaceutical Society of Japan in Biological & Pharmaceutical Bulletin
- Vol. 26 (10) , 1393-1397
- https://doi.org/10.1248/bpb.26.1393
Abstract
In normal mice, plasma histamine levels were 29.4±10.1 pmol/ml. When 0.1 μg of lipopolysaccharide (LPS) was intravenously injected into Propionibacterium acnes (P. acnes)-primed ICR mice, histamine levels increased remarkably to 61.2±15.9 pmol/ml (pppP. acnes plus LPS induction of liver injury.Keywords
This publication has 34 references indexed in Scilit:
- The resistance of P. acnes -primed interferon γ-deficient mice to low-dose lipopolysaccharide-induced acute liver injuryHepatology, 2002
- Towards Understanding Mechanisms of Drug Action and Functions of the Body on the Molecular Level. Studies on histamine with L-histidine decarboxylase, a histamine-forming enzyme, as a probe: from purification to gene knockout.Folia Pharmacologica Japonica, 2001
- Contribution of CD14 to Endotoxin-Induced Liver Injury May Depend on Types of Macrophage Activation in RatsBiochemical and Biophysical Research Communications, 1998
- Histamine modulates the acute phase response at multiple pointsImmunology Today, 1994
- Histamine enhances interleukin (IL)-1-induced IL-1 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist.Journal of Clinical Investigation, 1993
- Increased 5–Lipoxygenase Activity in Massive Hepatic Cell Necrosis in the Rat Correlates With Neutrophil InfiltrationHepatology, 1992
- Histamine Modulates the Interleukin-6-Regulated Acute Phase Protein Synthesis in Cultured Murine HepatocytesScandinavian Journal of Immunology, 1992
- Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors.The Journal of Experimental Medicine, 1991
- Proliferation and Phenotypic Expression of Non-Parenehymal Liver CellsScandinavian Journal of Gastroenterology, 1988
- Experimental study on the development of liver cell carcinoma. Role of histamine in chronic liver injury.The Keio Journal of Medicine, 1975