Melanosis Coli
- 1 January 1983
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 118 (1) , 62-64
- https://doi.org/10.1001/archsurg.1983.01390010048011
Abstract
• In 30 cases of colonic neoplasia associated with melanosis coli, proliferating or neoplastic colonic epithelium was notable within the melanotic colons by virtue of a striking absence of pigmentation. Microscopically this characteristic was found to be due to an absence or diminution of pigment-laden macrophages in the lamina propria underlying such lesions. Therefore, the absence of pigment-laden macrophages can be considered a marker for abnormally proliferating epithelium. This characteristic may denote a cellular or humoral change mediated by macrophages in association with neoplastic epithelium. (Arch Surg1983;118:62-64)Keywords
This publication has 2 references indexed in Scilit:
- Analysis of 6, 293 Routine ProctosigmoidoscopiesThe Tohoku Journal of Experimental Medicine, 1976
- Melanosis coli: Studies of the toxic effects of irritant purgativesThe Journal of Pathology, 1975