ALTERATIONS OF THYROID FUNCTION IN SEVERE HEART DISEASE, AS MEASURED BY I131TECHNIQUES

Abstract
A study of 18 patients with severe heart disease following administration of an I131 tracer showed the following alterations in thyroid function compared with euthyroid controls. 1) a decrease in the 24-hour and 72-hour plasma levels of PBI131, 2) a decrease in the 24-hour conversion ratio, and 3) a pronounced increase in salivary I131 activity at twenty-four hours. The thyroidal uptake of I131 remained the same as in euthyroid subjects. Data on hypothyroid and hyperthyroid patients are listed for comparison.