Bovine Enterovirus CPE at Different Multiplicities of Infection in the Absence of Viral RNA Synthesis
- 31 December 1978
- journal article
- research article
- Published by S. Karger AG in Intervirology
- Vol. 11 (4) , 255-260
- https://doi.org/10.1159/000149042
Abstract
When bovine enterovirus (BEV) RNA synthesis was inhibited by 2-(α-hydroxy-benzyl)-benzimidazole (HBB), an increase in MOI was accompanied by an enhancement of cytopathology. Since BEV RNA synthesis is inhibited and BEV protein synthesis is allowed to proceed in the presence of HBB, these results support the concept that proteins play a role in the development of cytopathology independently of viral double-stranded RNA.Keywords
This publication has 10 references indexed in Scilit:
- Interferon, double-stranded RNA, and protein phosphorylation.Proceedings of the National Academy of Sciences, 1976
- Relation between the adsorption to cells and antigenic properties in poliovirus particlesVirology, 1968
- Cytopathology of mengovirus infection II. Proliferation of membranous cisternaeVirology, 1967
- Effects on host cell metabolism following synchronous infection with poliovirusVirology, 1965
- Studies on the mechanism of poliovirus-induced cell damageVirology, 1965
- Evidence for uncoupled synthesis of viral RNA and viral capsidsVirology, 1964
- Inhibition of host cell macromolecular synthesis by high multiplicities of poliovirus under conditions preventing virus synthesisJournal of Molecular Biology, 1964
- ACTIVATION OF LYSOSOMAL ENZYMES IN VIRUS-INFECTED CELLS AND ITS POSSIBLE RELATIONSHIP TO CYTOPATHIC EFFECTSThe Journal of Experimental Medicine, 1963
- CYTOPATHOLOGY OF VIRUS INFECTION1962
- Infectivity of ribonucleic acid of poliovirus on HeLa cell monolayersVirology, 1958