The Convergence of Murein Recycling Research with β-Lactamase Research
- 1 January 1996
- journal article
- research article
- Published by Mary Ann Liebert Inc in Microbial Drug Resistance
- Vol. 2 (1) , 105-112
- https://doi.org/10.1089/mdr.1996.2.105
Abstract
The story of how investigation of Escherichia coli cell wall elongation evolved into a study of murein recycling and how this led to the discovery that ampG and ampD were required for both murein recycling and β-lactamase regulation is chronicled. Preliminary information on two other genes believed to be involved in recycling, nagZ, the structural gene for β-N-acetylglucosaminidase, and tpl, the presumed structural gene for the hypothetical tripeptide-adding enzyme, is presented. The possibility that recycling of murein fragments serves a signaling function is discussed.Keywords
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