Effect of corticosterone and triiodothyronine on (Na++K+)-adenosine triphosphatase activity in rat submandibular gland
- 1 December 1983
- journal article
- research article
- Published by Springer Nature in Pflügers Archiv - European Journal of Physiology
- Vol. 399 (4) , 255-258
- https://doi.org/10.1007/bf00652748
Abstract
The present study concerns the effect of glucocorticoids and triiodothyronine (T3) on rat salivary (Na++K+)-adenosine triphosphatase (NaK-ATPase). The results indicate that corticosterone increases submandibular gland NaK-ATPase activity with a single dose of hormone and with two daily doses on three successive days. Multiple injections of dexamethasone also increases submandibular and sublingual gland NaK-ATPase activity. The effect of glucocorticoids on salivary NaK-ATPase is selective since Mg-ATPase shows no significant differences under different steroidal states. We subsequently investigate the possibility of interaction between the effects of corticosterone and triiodothyronine on submandibular gland NaK-ATPase activity. Our studies indicate that each of these hormones increases NaK-ATPase activity in the absence of the other.Keywords
This publication has 33 references indexed in Scilit:
- Effect of triiodothyronine on (Na++K+)-adenosine triphosphatase and (Na++Mg2+)-dependent phosphorylated intermediate in rat salivary glandsPflügers Archiv - European Journal of Physiology, 1981
- Mechanisms of activation of renal (Na+ + K+)-ATPase in the rat Effects of acute and chronic administration of dexamethasoneBiochimica et Biophysica Acta (BBA) - Biomembranes, 1981
- Effect of thyroid hormones on the level of the hepatic mRNA for α2u globulinBiochemistry, 1976
- Messenger RNA for glutamine synthetase: Its partial purification, translation in a cell-free system and its regulation by hydrocortisoneBiochemical and Biophysical Research Communications, 1976
- Thyroid Hormone Action in Cell Culture: Demonstration of Nuclear Receptors in Intact Cells and Isolated NucleiProceedings of the National Academy of Sciences, 1973
- Subcellular mechanisms in the action of adrenal steroidsThe American Journal of Medicine, 1972
- A microperfusion investigation of sodium resorption and potassium secretion by the main excretory duct of the rat submaxillary glandPflügers Archiv - European Journal of Physiology, 1967
- An enzymatic basis for active cation transport in the parotid glandJournal of Cellular and Comparative Physiology, 1963
- Studies on sodium-potassium-activated adenosine triphosphataseArchives of Biochemistry and Biophysics, 1961
- The influence of some cations on an adenosine triphosphatase from peripheral nervesBiochimica et Biophysica Acta, 1957