Generalized Hypersensitivity Reaction to Intravesical Thiotepa and Doxorubicin

Abstract
We describe an unusual case of pruritus after intravesical thiotepa, and diaphoresis, shortness of breath, chills and pruritus following intravesical doxorubicin therapy. Such generalized allergic reactions occur uncommonly after bladder instillation of thiotepa or doxorubicin.