Multiple halo neurofibromas

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Abstract
The 2nd case of multiple halo neurofibromatosis is reported. Halo neurofibromas are rare benign tumors that appear on the neck and trunk of adults. The clinical and histopathological differential diagnosis of the other neuroectodermally derived halo lesions, such as neural nevus, nevocellular nevus, spindle and epithelioid cell nevus, blue nevus and malignant melanoma, is also considered. An autoimmune hypothesis is proposed to explain the depigmentation in the halo neurofibroma. The fact that the patient had cafe au lait spots containing giant pigment granules probably indicates that he also had neurofibromatosis.