TERMINATION OF ABNORMAL INTRAUTERINE PREGNANCIES WITH INTRAMUSCULAR ADMINISTRATION OF DIHOMO 15 METHYL PROSTAGLANDIN F2α

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Abstract
A synthetic compound, 2a, 2b dihomo 15 (S) 15 methyl prostaglandin F 2 alpha methyl ester given 8-hourly by intramuscular injection was used to terminate pregnancies in 72 patients with a missed abortion, intrauterine fetal death, molar or anencephalic pregnancies. Treatment was successful in all cases. A 4 mg dose of loperamide given orally at 15 to 30 minutes before the injection of prostaglandin analogue prevented diarrhoea as a side effect.