Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride

Abstract
Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride in pyridine produced adenosine 5′-phosphoramidates in good yields under mild conditions, it is interesting that nucleophilic attack of amino acid methyl esters only occurred on α-phosphorus of ADP.
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