Abstract
In the nursery of an Austrian hospital, five newborns accidentally received 10 % natrium chloride solution by infusion or oral feeding. Because of wrong labelling by the hospital pharmacy the solution was taken for 10% glucose. In all five newborns, bradycardia, edemas, cyanosis and cramps occurred. In all cases, autopsy revealed a fatal haemorrhagic encephalopathy and more or less extended haemorrhages of the lungs, the kidneys and the liver. There was no suppurative pneumonia and no arteriitis. The intracerebral bleedings, thromboses and necroses may be provoked by tissue shrinking caused by hypernatriaemic dehydration. The cerebral lesions again cause hyperosmolarity leading to death in most cases. Peritoneal dialysis which may be life-saving in some cases, unfortunately has not been performed in the present cases. Fünf Neugeborene wurden in der Gebärstation eines österreichischen Krankenhauses irrtümlich mit einer 10 % Kochsalzlösung statt mit einer 10 % Glukoselösung infundiert beziehungsweise oral gefüttert. Bei allen fünf Neugeborenen kam es zu einer tödlichen hämorrhagischen Enzephalopathie und zum Teil auch zu ausgedehnten Blutungen in Lungen, Nieren und Leber. Die Pathogenese der Veränderungen wird diskutiert.

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