Inheritance of posterior choanal atresia

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Abstract
Posterior choanal atresia (PCA) was observed in a brother and sister and their paternal aunt from a Yemenite family in which several cousin marriages had taken place. Such an occurrence may be compatible with autosomal recessive inheritance. In some cases PCA evidently is an autosomal dominant trait. However, its mostly sporadic occurrence with sex preference suggests that multifactorial determination may play an important role.

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