ENZYMATIC SYNTHESIS OF THE SALMONELLA 0-ANTIGEN
Open Access
- 1 November 1964
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 52 (5) , 1302-1309
- https://doi.org/10.1073/pnas.52.5.1302
Abstract
Enzymatic synthesis of the galactosyl-mannosyl-rhamnosyl repeating unit of the Salmonella anatum O-antigen from nucleotide sugar precursors is described. Long chains are formed with little or no terminal labeling of the lipopolysaccharide. The product is largely precipitable by anti-O-antiserum and gives rise to the typical oligosaccharide pattern of the antigen following partial acid hydrolysis.Keywords
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