Mouse Ear PCA as a Model for Evaluating Antianaphylactic Agents
Open Access
- 1 January 1984
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 74 (1) , 91-92
- https://doi.org/10.1159/000233523
Abstract
Passive cutaneous anaphylaxis (PCA) reaction elicited in ears of male ddY mice was studied by means of assessing dye leakage. In the ear, PCA reaction was more sensitive and reproducible than that in the dorsal skin. The reaction was significantly suppressed by ketotifen, one of antianaphylactic agents.Keywords
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