The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum
Open Access
- 1 January 2007
- journal article
- Published by Springer Nature in BMC Genomics
- Vol. 8 (1) , 327
- https://doi.org/10.1186/1471-2164-8-327
Abstract
Members of the cys-loop ligand-gated ion channel (cys-loop LGIC) superfamily mediate chemical neurotransmission and are studied extensively as potential targets of drugs used to treat neurological disorders such as Alzheimer's disease. Insect cys-loop LGICs are also of interest as they are targets of highly successful insecticides. The red flour beetle, Tribolium castaneum, is a major pest of stored agricultural products and is also an important model organism for studying development.Keywords
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