Body mass index and survival in incident dialysis patients: the answer depends on the question

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Abstract
In a recent issue of the journal, Johansen et al (1) examined an important question—What is the association of body size with survival adjusted for muscle mass in incident dialysis patients? However, there are really 3 questions: 1) What is the independent association between muscle mass and mortality, 2) What is the independent association between BMI and mortality, and 3) How does mortality vary across different levels of BMI and muscle mass combined. Based on the answer to the question posed by Johansen et al, inferences on whether body composition influences the survival of incident dialysis patients with a high BMI could not be drawn.

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