Plasma Amino Acid Concentration and the Regulation of Albumin Synthesis
Open Access
- 1 December 1969
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 22 (12) , 1559-1562
- https://doi.org/10.1093/ajcn/22.12.1559
Abstract
Amino acid concentration as a factor regulating albumin synthesis in protein-depletion states was tested by perfusing livers with blood from malnourished animals in which the concentration of branched-chain amino acids was reduced. These livers synthesized significantly less albumin than did livers perfused with normal blood. Addition of branched-chain amino acids to the perfusate restored the albumin synthesis rate to normal.Keywords
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