Spontaneous Systemic Lupus Erythematosus and Acetylator Phenotype
- 11 January 1977
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 201 (1-6) , 223-226
- https://doi.org/10.1111/j.0954-6820.1977.tb15686.x
Abstract
Fifteen patients with spontaneous systemic lupus erythematosus (SLE) were phenotyped by determination of plasma isoniazid (INH) half-life. Seven patients had signs of renal insufficiency. Of the 15 patients, 13 were slow and only 2 rapid acetylators. No correlation was found between the plasma INH half-lives and the renal function. Thus, there is the same marked predominance of slow acetylators in patients with spontaneous SLE as in patients with the drug-induced SLE-like syndrome.This publication has 20 references indexed in Scilit:
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