VIP nerve fibres around peripheral blood vessels
- 1 May 1981
- journal article
- research article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 112 (1) , 65-70
- https://doi.org/10.1111/j.1748-1716.1981.tb06783.x
Abstract
By immunocytochemistry nerve fibres containing vasoactive intestinal polypeptide (VIP) were demonstrated around many peripheral blood vessels in the cat. Such nerve fibres were particularly numerous around arteries in the upper respiratory, gastrointestinal and genito‐urinary tracts. They were less numerous around large arteries and veins and seemed to be absent from blood vessels in the liver, spleen and kidney. VIP nerve fibres were few around blood vessels in skeletal muscle and absent in coronary arteries. Administration of VIP in vitro relaxed all arteries tested provided they had been given an increased tone, for instance by preincubation with PGF2α. It is likely that VIP in vascular nerve fibres may participate in the regulation of systemic and local blood flow.Keywords
This publication has 31 references indexed in Scilit:
- Immunohistochemical localization and vascular effects of vasoactive intestinal polypeptide in skeletal muscle of the catCell and tissue research, 1980
- DISTRIBUTION OF VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) IN THE PORCINE CENTRAL NERVOUS SYSTEMJournal of Neurochemistry, 1978
- Occurrence and Distribution of Vip Nerves in the Nasal Mucosa and Tracheobronchial WallActa Oto-Laryngologica, 1978
- Peptidergic (vasoactive intestinal peptide) nerves in the genito-urinary tractNeuroscience, 1977
- Vasoactive Intestinal Polypeptide Occurs in Nerves of the Female Genitourinary TractScience, 1977
- Vasoactive intestinal polypeptide and the nervous system: Immunohistochemical evidence for localization in central and peripheral neurons, particularly intracortical neurons of the cerebral cortexNeuroscience Letters, 1977
- Occurrence of nerves containing vasoactive intestinal polypeptide immunoreactivity in the male genital tractLife Sciences, 1977
- POSSIBLE DUAL ROLE FOR VASOACTIVE INTESTINAL PEPTIDE AS GASTROINTESTINAL HORMONE AND NEUROTRANSMITTER SUBSTANCEThe Lancet, 1976
- Pharmacological Characterization of Adrenergic Alpha and Beta Receptors Mediating the Vasomotor Responses of Cerebral Arteries Ir VitroCirculation Research, 1974
- Relaxations of the isolated portal vein of the rabbit induced by nicotine and electrical stimulationBritish Journal of Pharmacology, 1970