Premenopausal Bone Loss — A Risk Factor for Osteoporosis

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Abstract
Low bone mass is a major determinant of the osteoporotic fractures that are becoming increasingly common as the population ages. Low bone mass at the time of a fracture may result from either low peak bone mass, which is attained in the third or fourth decade of life, or subsequent bone loss, especially that occurring after the menopause. Peak bone mass is the more important variable early after loss begins; the rate of loss becomes increasingly important later in life.1 The importance of peak bone mass as a determinant of subsequent bone mass is the reason that a single measurement . . .