Bone Formation within Porous Hydroxylapatite Implants in Human Periodontal Defects

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Abstract
Tissue samples from three subjects who had periodontal defects treated with a porous hydroxylapatite implant were investigated using light microscopy and scanning electron microscopy. The 3‐month specimen showed connective tissue infiltration through the pores and a narrow zone of bone formation present along the walls of the pores. At 4 months, continued evidence of bone deposition was present with osteocytes, osteoblasts and organization of collagen fibers apparent throughout the implant. The 6‐month implant had further evidence of continued bone formation with lamellar bone being the major component within the pores.