SALMONELLA SPECIFIC ANTIBODIES IN SERUM AND SYNOVIAL FLUID IN PATIENTS WITH REACTIVE ARTHRITIS

Open Access

1 January 1992

journal article
research article
Published by Oxford University Press (OUP) in Rheumatology

Vol. 31 (1) , 25-29
https://doi.org/10.1093/rheumatology/31.1.25

Abstract

The occurrence of Salmonella specific antibodies was analysed in paired serum and synovial fluid samples from 12 patients with Salmonella triggered reactive arthritis. The antibody concentration of IgA₂ subclass in synovial fluid exceeded that of serum in 8 of the 12 pairs studied, compared to 0–3 in the other immunoglobulin classes and subclasses. This finding indicates intra-articular production of IgA₂ class antibodies against the triggering microbe.

Keywords

EIA
IMMUNOGLOBULIN CLASS
IMMUNOGLOBULIN SUBCLASS
LIPOPOLYSACCHARIDE
SALMONELLA
REACTIVE ARTHRITIS
ANTIBODY

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