4-Amino derivatives of the Hsp90 inhibitor CCT018159
- 9 February 2006
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 16 (9) , 2543-2548
- https://doi.org/10.1016/j.bmcl.2006.01.099
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitorsBioorganic & Medicinal Chemistry Letters, 2005
- Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based DesignJournal of Medicinal Chemistry, 2005
- Crystal structures of human HSP90α-complexed with dihydroxyphenylpyrazolesBioorganic & Medicinal Chemistry Letters, 2005
- Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 IsoformsChemistry & Biology, 2004
- Overview: Translating Hsp90 Biology into Hsp90 DrugsCurrent Cancer Drug Targets, 2003
- The Clinical Applications of Heat Shock Protein Inhibitors in Cancer - Present and FutureCurrent Cancer Drug Targets, 2003
- Crystal Structure and Molecular Modeling of 17-DMAG in Complex with Human Hsp90Chemistry & Biology, 2003
- HSP90 as a new therapeutic target for cancer therapy: the story unfoldsExpert Opinion on Biological Therapy, 2002
- Molecular Interactions in Solution: An Overview of Methods Based on Continuous Distributions of the SolventChemical Reviews, 1994
- General atomic and molecular electronic structure systemJournal of Computational Chemistry, 1993