Evidence that ribosomal protein S10 participates in control of transcription termination.
- 1 February 1981
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 78 (2) , 1115-1118
- https://doi.org/10.1073/pnas.78.2.1115
Abstract
The isolation of an Escherichia coli K-12 strain with a mutation, nusE71, that results in a change in ribosomal protein S10 is reported. Phage .lambda. fails to grow in hosts carrying the nusE71 mutation because the .lambda.N gene product is not active. The N product regulates phage gene expression by altering transcription complexes so that they can overcome termination barriers. A ribosomal protein is apparently involved in antitermination of transcription.This publication has 32 references indexed in Scilit:
- Specificity of the bacteriophage lambda N gene product (pN): Nut sequences are necessary and sufficient for antitermination by pNCell, 1979
- Coliphage λnutL−: A unique class of mutants defective in the site of gene N product utilization for antitermination of leftward transcriptionJournal of Molecular Biology, 1978
- Control of Transcription TerminationAnnual Review of Biochemistry, 1978
- The relationship between function and DNA sequence in an intercistronic regulatory region in phage λNature, 1978
- Differential effect of phage regulator functions on transcription from various promoters: Evidence that the P22 gene 24 and the λ gene N products distinguish three classes of promotersJournal of Molecular Biology, 1975
- Altered reading of genetic signals fused to the N operon of bacteriophage λ: Genetic evidence for modification of polymerase by the protein product of the N geneJournal of Molecular Biology, 1974
- Gene N regulator function of phage λimm21: Evidence that a site of N action differs from a site of N recognitionJournal of Molecular Biology, 1973
- Separation and radioautography of microgram quantities of ribosomal proteins by two‐dimensional polyacrylamide gel electrophoresisFEBS Letters, 1973
- Relationship between the N function of bacteriophage λ and host RNA polymeraseJournal of Molecular Biology, 1972
- Integration-negative mutants of bacteriophage lambdaJournal of Molecular Biology, 1968