Abstract
RECENT advances in knowledge and understanding of the nature and functional disturbances of pyelonephritis have led to more rational therapy. The purpose of this communication is to review this progress.Pyelonephritis, the commonest of all renal diseases, is due to bacterial infection of the kidney. In infections of the urinary tract, the kidney must always be assumed to be involved until proved otherwise, since there is often no reliable method of differentiating infection of the lower and upper urinary tract. However, urethral, prostatic and rarely bladder infections may occur without renal involvement.PathogenesisRecently, Beeson1 has brought together and appraised . . .