Vogt-Koyanagi-Harada disease occurring during interferon alpha therapy for chronic hepatitis C
- 1 November 2004
- journal article
- case report
- Published by Springer Nature in The Esophagus
- Vol. 39 (11) , 1106-1109
- https://doi.org/10.1007/s00535-004-1452-4
Abstract
Retinal abnormalities, including retinal hemorrhage and "cotton-wool" spots, often occur within the first 8 weeks in the course of interferon therapy in patients with chronic hepatitis C. Here, we describe a case of Vogt-Koyanagi-Harada disease occurring 4 months after the start of interferon alpha treatment, probably induced by the immunomodulatory effects of interferon. Therefore, we conclude that chronic hepatitis C patients, especially people with darkly pigmented skin, need to be closely monitored for ophthalmologic complications, by periodic check-up of the optic fundi, for a prolonged period, during interferon treatment.Keywords
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