Successful Prophylaxis of Clostridium perfringens Endophthalmitis

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Abstract
Clostridium perfringens, an anaerobic, gram-positive Bacillus, is an infrequent pathogen in endophthalmitis. Typically, ocular infection with this organism is rapidly destructive and accompanied by severe visual loss. We recently treated a patient with ocular trauma and C perfringens contamination of the vitreous who recovered 20/25 visual acuity. Report of a Case. —A 24-year-old male farm worker was referred to the Southern Illinois University Eye Center (Springfield) after penetration of the right eye with a manure-contaminated nail. His visual acuity was measured at hand motions at 1 ft in the right eye and 20/20 in the left eye. Slit-lamp biomicroscopy of the right eye revealed conjunctival hyperemia, a 4.5-mm stellate corneoscleral laceration that did not involve the visual axis, and iris prolapse with the pupil peaked toward the wound. The anterior chamber was flat and the lens was opacified, precluding visualization of the vitreous and retina. The left eye was normal.

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