A Near Miss — Osler's Early Description of Cushing's Syndrome with, Regrettably, No Post-Mortem Examination
- 15 May 1980
- journal article
- other
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 302 (20) , 1153-1155
- https://doi.org/10.1056/nejm198005153022021
Abstract
In May 1898, William Osler read a paper before the 24th annual meeting of the American Neurological Society. The paper was published in the Journal of Nervous and Mental Diseases in February 1899.1 The title of the paper was "An Acute Myxcedematous Condition, with Tachycardia, Glycosuria, Melæna, Mania, and Death." The article was based on the case report of a male patient he had seen in February and March of 1897. One of the more striking aspects of the clinical picture was a gain in weight of 37 pounds (17 kg) in the three months from October to the end . . .Keywords
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- CUTANEOUS STRAE, PURPURA, HIGH BLOOD-PRESSURE, AMENORRHŒA AND OBESITY, OF THE TYPE SOMETIMES CONNECTED WITH CORTICAL TUMOURS OF THE ADRENAL GLANDS, OCCURRING IN THE ABSENCE OF ANY SUCH TUMOUR*—WITH SOME REMARKS ON THE MORPHOGENETIC AND HORMONIC EFFECTS OF TRUE HYPERNEPHROMATA OF THE ADRENAL CORTEX.British Journal of Dermatology, 1926
- AN ACUTE MYXŒDEMATOUS CONDITION, WITH TACHYCARDIA, GLYCOSURIA, MELÆNA, MANIA, AND DEATHJournal of Nervous & Mental Disease, 1899